PERFIL DE RESISTÊNCIA DAS BACTÉRIAS GRAM-NEGATIVAS COMUMENTE ASSOCIADAS À INFECÇÕES DO TRATO URINÁ- RIO EM IDOSOS EM GOIÂNIA – GO, NO PERÍODO DE 2011- 2015

Abstract

The urinary tract infections (UTI) are one of the most common types of infection, both community as nosocomial, the ITU is caused by bacteria are more common in men and in. The study was descriti-vo retrospective and prospective type, from 2011 to 2016 were analyzed from 3388 antibiograms of ITU of Community origin in the elderly. The age of patients ranged from 60 to 100 years, with a mean age of 73 years, and 77.28% occurred in women and 22.72% in men. The microranalyzed organisms were Escherichia coli (75.65%) with 80.72% by Women's res and 19.28% in men, followed by Klebsiella pneumoniae (16.59%) with 66.73% infection 33.27% in women and in men. Proteus spp. It was respon-sible for 5.70% cases, with 70.47% occurred in women and 29.53% in ho-mens. Enterobacter spp. It was the causative organism of UTI in 2.07%; 45.71% women and 54.29% in men. The highest prevalence of resistance to E. coli were to sulfonamide (40.54%), Ciprofloxacin (35.04%), Nalidixic acid (34.92%), Cephalosporins 1st Generation (31,45%), Norfloxacin (24 , 50%), Penicillin (23.68%) and 3rd generation cephalosporins (12.29%), an increase in the evolution of resistance to cephalosporins 2nd generation (p = 0.0074). For K. pneumoniae, the major resistance prevalence occurs to ram for Norfloxacin (16.73%), cephalosporins 3rd Generation (20.46%), Aci-of Nalidixic (26.87%), Cephalosporins 1st Generation (29 , 00%), Penicillin (33.99%), sulfonamide (35.05%), Nitrofurantoin (37.90%), Gemifloxacin (46.09%) and ofloxacin (46.09%) with increased resistance evolution Carbapenems for (p = 0.0271) and Cephalosporins 1st generation (p = 0.0496). Proteus spp., The major resistance prevalences were to Gati-floxacina (12.95%), Norfloxacin (12.95%), penicillins (14.51%), cephalosporins on the 2nd Generation (21.24%) , sulfonamide (36.27%), Cephalosporins 1st Ge-feed (38.86%), Gemifloxacin (46.11%), ofloxacin (46.11%), nitrofurantoin (76.68%), Nalidixic acid (81 , 87%) and levofloxacin (81.87%). For Enterobac-have spp., The major resistance prevalences were compared to Cefalospo-mandarins of 4th Generation (15.71%), Gatifloxacin (21.43%), Norfloxacin (21.43%), Ciprofloxacin (28.57 %), Moxifloxacin (28.57%), Nitrofurantoin (31.43%), 3rd generation cephalosporins (32.86%), sulfonamide (38.57%), Gemifloxacin (42.86%), ofloxacin (42, 86%) 1st generation cephalosporins (44.29%), nalidixic acid (77.14%), Levofloxacin (77.14%) and Penicillins (97.14%) with au-ment in the evolution of resistance to cephalosporins 2nd Generation (p = 0.0057). For empiric treatment of complicated UTI due to the found resistance to the antimicrobials of choice, the aminoglycosides, Carbapenems and monobactam can be used until they are met, the causative agents of infection and susceptibility to tested Antimicro-bianos and should be replaced by re-duced antimicrobial spectrum, but with high power.