EFEITOS DE ATIVIDADE FÍSICA INTENSA NOS NÍVEIS SÉRICOS DE CREATINA QUINASE, IL-6 E PROTEÍNA C-REATIVA EM ATLETAS

Abstract

The Environmental Walk takes place every year in Goiás-Brazil, this is an event that athletes walk along 310 Km in 5 days, stimulating the environmental awareness, specially, the Cerrado Biome. During the strenuous physical activity, of long way, physiological changes occur, triggering the release of inflammation-related markers. The present study had as objective to verify, in athletes of the Environmental Walk of 2014. the behavior of serum levels of the CK, PCR e IL-6 markers, before and during the walk.Venous Blood samples were taken from 24 athletes of mankind who were on the environmental walk and it was evaluated the serum levels of CK, PCR e IL-6. The 24 athletes were about 45,1 + 8,50. The medium Serum levels of PCR had increased from 1,22 + 1,28 on the baseline to 13,1 + 13,9, after the fourth walking day (+973,8%; p < 0,001). The Serum levels of IL-6 had increased from 2,19 pg/ml (DP + 1,96), on the baseline to 4,59 pg/ml (DP + 3,95), at the end of the walk (+109,6%; p < 0,001). Similarly, it was verified a significant increasing on the concentration of enzyme CK on the evaluated periods. The medium Serum levels increased from 588,6 + 1.024,5 to 1.473,2 + 1.797,6 (+150,3%; p < 0,001). The present study evidenced progressive tissue injury estimated by the CK Enzyme Serum levels. However, the subsequent inflammatory response, evidenced by the IL-6 and PCR levels, showed itself limited, getting the maximum expression on the second and third day respectively, decaying itself since then. Such results contribute to the comprehension of the physiological alterations generated during the physical stress and the capacity of the organism of reestablishing the normal levels.