Doença cardiovascular e doença vascular periférica: aspectos sócio-ambientais e análise estrutural de resistência à fadiga de um novo protótipo de stent vascular periférico recoberto

Abstract

Peripheral vascular disease, an important component of cardiovascular diseases, represents a considerable cause of death and hospitalization due to chronic disease in Brazil and in the world, causing an overload on health systems and great financial impact. In the last decades, there has been a change in the surgical treatment of peripheral circulatory diseases, with a significant increase in minimally invasive endovascular procedures and in the use of peripheral stents. New intraluminal devices have been developed with structural improvements in order to increase their effectiveness and durability, with the laboratory tests of fatigue resistance being fundamental in this process. The objective of this study was to perform the structural analysis of fatigue resistance of a new model of covered peripheral vascular stent. The evaluation of the prototype was performed by using two methods: in vitro accelerated fatigue test (AFT) and computational analysis using the finite element method (FEM). A total of 6 prototypes analyzed macroscopically and microscopically before and after AFT, as well as computational analysis of the model using Solidworks® and Abaqus® software in its simulation. The prototypes submitted to the accelerated fatigue test were successful in fatigue resistance after a total of 400 million cycles of accelerated fatigue and the computational analysis of the proposed model, after validation, was able to confirm safety and identify the points of greatest stress / strain under simulated conditions of pulsatile arterial flow in stenosed peripheral artery. Based on this work, it is concluded that the studied model of covered peripheral vascular stent presents adequate structural resistance to the analyses performed, in accordance with international standards